EVERYTHING ABOUT CONOLIDINE ALKALOID FOR CHRONIC PAIN

Most recently, it's been discovered that conolidine and the above derivatives act on the atypical chemokine receptor three (ACKR3. Expressed in similar spots as classical opioid receptors, it binds to a big selection of endogenous opioids. Unlike most opioid receptors, this receptor functions to be a scavenger and will not activate a second messeng